4th Year Undergraduate Research Thesis Opportunity #2

Investigation into the Structure of the Oyster Alternative Oxidase Protein

An undergraduate student position is available to conduct a BI499 or HE490 thesis research project in the McDonald lab in the Department of Biology at Laurier. The McDonald lab prides itself on being a diverse and friendly working environment.

Description of the Project:

Research in our lab focuses on the mitochondrial protein alternative oxidase (AOX) which is involved in the electron transport system in mitochondria. This project will focus on developing a protocol for isolating mitochondria from the yeast Saccharomyces cerevisiae that are expressing the oyster AOX protein. These yeast mitochondria will then be exposed to various chemical cross-linkers in order to determine whether oyster AOX is monomeric, dimeric, or oligomeric by using protein gel electrophoresis and Western blots.

Skills Required:

Ability to effectively conduct literature searches and to analyze and synthesize information from primary research papers.

Knowledge of the theory of protein gel electrophoresis and Western blotting techniques.

Attention to detail and ability to work safely in a biological laboratory.

Strong written and oral communication skills.

Effective time-management and project management skills.

Highly self-motivated and resilient in the face of project challenges.

Interested students should email Dr. Allison McDonald at amcdonald@wlu.ca by Jan. 31, 2017 with a resume/CV and to set up a time for an interview in early February.

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